In vitro anticancer screening of South African plants

In vitro anticancer screening of South African plants

28/10/2008· Plant species were collected throughout South Africa and voucher specimens were deposited and identified at the South African National Biodiversity Institute. Plant extracts were prepared and screened for in vitro anticancer activity against a panel of three human cell lines (breast MCF7, renal TK10 and melanoma UACC62) at the CSIR. Plant

In vitro anticancer screening of South African plants.

28/10/2008· In vitro anticancer screening of South African plants. Fouche G(1), Cragg GM, Pillay P, Kolesnikova N, Maharaj VJ, Senabe J. Author information: (1)Biosciences, Council for Scientific and Industrial Research, PO Box 395, Pretoria, Gauteng 0001, South Africa. [email protected]

In vitro anticancer screening of South African plants

Request PDF on ResearchGate In vitro anticancer screening of South African plants The purpose of the present study is to evaluate South African plants for their anticancer activity. Plant

In vitro Screening of Nigella sativa Seeds for Antifungal

The purpose of the present study is to evaluate South African plants for their anticancer activity. Plant species were collected throughout South Africa and voucher specimens were deposited and

NMR-based metabolomic study of medicinal plants used

In vitro antiplasmodial screening of ethnopharmacologically selected South African plant species used for the treatmen t of malaria. Journal of Ethnopharmacology 156: 370 ± 373. Scientific publications in preparation: Bapela, M.J., Meyer, J.J.M., Kaiser, M., 2015. Antileishmanial activity of select ed South African indigenous plant species.

In vitro cytotoxicity, antioxidant and anti-inflammatory

Although the natural product approach to discovery of anticancer agents has been successful worldwide, in South Africa there are still only a few reports on medicinal plants used in cancer therapy, irrespective of the fact that some plants from this region are known to exhibit cytotoxicity towards cancer cells (Fouche et al., 2008).

Journal of Ethnopharmacology Ethnobotany in South

In vitro evidence of phyto-synergy for plant part combinations of Croton gratissimus (Euphorbiaceae) used in African traditional healing S.F. van Vuuren, A.M. Viljoen Pages 700-704

Evaluation of traditionally used medicinal plants for

The anticancer activity of four medicinally used plants against cervical and epidermoid cancer. • S. jambos showed 100% viral inhibition at a non-toxic concentration of 50 μg/ml.. S. jambos significantly inhibited cyclooxygenase-2 (COX-2) and the DPPH free radical.. The collective data of S. jambos shows its potential as a chemopreventive and anticancer agent.

In vitro Screening of Nigella sativa Seeds for Antifungal

The purpose of the present study is to evaluate South African plants for their anticancer activity. Plant species were collected throughout South Africa and voucher specimens were deposited and

Ethnobotanical survey and cytotoxicity testing of plants

24/03/2010· Although much screening of medicinal plants for potential anticancer activity has occurred in the last fifty years, the study of ethnopharmacological leads from African medicinal plants has not been realized as fully as from other traditional societies such as India and China.

NMR-based metabolomic study of medicinal plants used

In vitro antiplasmodial screening of ethnopharmacologically selected South African plant species used for the treatmen t of malaria. Journal of Ethnopharmacology 156: 370 ± 373. Scientific publications in preparation: Bapela, M.J., Meyer, J.J.M., Kaiser, M., 2015. Antileishmanial activity of select ed South African indigenous plant species.

Traditional Medicinal Plants for anticancer activity

Even if the plant is widely used in the traditional medicine system of South Africa, little work has been done in the identification and biological screening of the secondary metabolites of the

In vitro antibacterial and cytotoxic activity of leaf

29/11/2018· In vitro antibacterial and cytotoxic activity of leaf extracts of Centella asiatica (L.) Urb, Warburgia salutaris (Bertol. F.) Chiov and Curtisia dentata (Burm. F.) C.A.Sm medicinal plants used in South Africa

ANTHELMINTIC, ANTICANCER AND PHYTOCHEMICAL SCREENING

In vitro anthelmintic effects of Artemisia afra and Mentha longifolia against parasitic gastro-intestinal nematodes of livestock. The 41st Annual Parasitological Society of Southern Africa (PARSA) Conference, Bloemfontein, South Africa, 1–3 October 2012. 2. Molefe NI, Tsotetsi AM, Ashafa AOT, Thekisoe OMM. In vitro anthelmintic

IN VITRO ANTICANCER SCREENING OF ASPARAGUS LARICINUS

IN VITRO ANTICANCER SCREENING OF ASPARAGUS LARICINUS EXTRACTS S. Mashele and N. Kolesnikova Faculty of Health and Environmental Studies, Central University of Technology, Free State, Private Bag X20539, Bloemfontein, RSA Bioprospecting, Biosciences, CSIR, PO Box 395, Pretoria, 0001, RSA Summary The aim of the present study was to determine the anticancer activity of Asparagus

Isoflavones from Calpurnia Aurea subsp. Aurea and Their

The isolated compounds were identified by NMR spectroscopy and the compounds were tested for their in vitro anticancer activity against breast (MCF7), renal (TK10) and melanoma (UACC62) human cell lines using an in house method developed at the CSIR, South Africa.

Evaluation of the antibacterial and anticancer activities

Fresh plant parts were collected in ORTDM, Eastern Cape Province, South Africa between July 2008 and February 2010. The plants were identified in the Kei herbarium, Walter Sisulu University, South Africa where voucher specimens have been deposited. Information on the selected herbs are presented in Table Table1 1 [13-19]. The air-dried plant

14740 publications and PDFs in Anticancer Screening

In the present study, preliminary in-vitro anticancer screening of the alcoholic extracts of leaves (LE) and flowers (FE) of Rhododendron arboreum was performed against Crown Gall tumor and MCF-7

In Vitro Assessment of Selected Medicinal Plants Used by

This plant grows from an enormous underground rhizome and is widely distributed in South Africa. 10 The traditional uses include treatment of various diseases in cows, including pneumonia, coughing, and tick-borne diseases. 12 S. pinnata (Asteraceae) can mostly be found on roadsides and ground like fields in Zimbabwe and South Africa. 13 The

In Vitro Anti-Proliferative Activity of Selected Plant

The extracts in vitro anti-proliferative activity against DU145 and 22Rv1 (Prostate cancer), HeLa (cervical cancer) and Vero (African green monkey), cancer cells was investigated using the MTT assay. In this study we found significant anti-proliferative activity of the organic extract of D. cinerea stem bark against the 22Rv1 extracts.

Toxicity and Antiviral Activities of Some Medicinal Plants

Genital herpes, usually caused by Herpes Simplex Virus type-2 (HSV-2), is the commonest sexually transmitted disease especially amongst rural women in Southern Africa including Zimbabwe. This predisposes them to HIV/AIDS infection, cancer and opportunistic infections (OIs). Current antiviral treatments are often cytotoxic and/or ineffective.

Gordon M. L. Cragg Semantic Scholar

In vitro anticancer screening of South African plants. Gerda Fouche, Gordon M. L. Cragg, P Parameswaran Pillay, Nataliya Kolesnikova, Vinesh J Maharaj, Jeremiah Senabe; Journal of ethnopharmacology ; 2008; AIM OF THE STUDY The purpose of the present study is to evaluate South African plants for their anticancer activity. MATERIALS AND METHODS Plant species were collected throughout South

Over 60% of currently used anti-cancer agents are derived

High throughput screening of South African plants for anti-cancer properties G Fouche, J Senabe, e Khorombi, n KoleSniKova, vJ maharaJ and r nthambeleni CSIR Biosciences, PO Box 395, Pretoria, 0001, South Africa Email: [email protected] csir.co.za IntroductIon Plants have a long history of use in the treatment of cancer and over 60% of

(PDF) In vitro evaluation of anticancer and antimicrobial

In vitro evaluation of anticancer and antimicrobial activity of selected medicinal plants from Ayurveda. P. Gacche. Download with Google Download with Facebook or download with email. In vitro evaluation of anticancer and antimicrobial activity of selected medicinal plants from Ayurveda. Download . In vitro evaluation of anticancer and antimicrobial activity of selected medicinal plants from

PHYTOCHEMICAL ANALYSIS AND IN-VITRO

The results of in-vitro cancer activity showed that Duranta erecta plant could be used in the treatment of leukemia and the demonstration of anticancer activity against Human Leukemia Cell Line HL-60 is an indication that there is the possibility of sourcing of new anticancer compounds from screened plant leading to the discovery of new compounds.

Isoflavones from Calpurnia Aurea subsp. Aurea and Their

The isolated compounds were identified by NMR spectroscopy and the compounds were tested for their in vitro anticancer activity against breast (MCF7), renal (TK10) and melanoma (UACC62) human cell lines using an in house method developed at the CSIR, South Africa.

(PDF) In vitro evaluation of anticancer and antimicrobial

In vitro evaluation of anticancer and antimicrobial activity of selected medicinal plants from Ayurveda. P. Gacche. Download with Google Download with Facebook or download with email. In vitro evaluation of anticancer and antimicrobial activity of selected medicinal plants from Ayurveda. Download . In vitro evaluation of anticancer and antimicrobial activity of selected medicinal plants from

African Plants WORLD BOTANICAL

Voucher specimens of plants from Kenya and Tanzania were identified by staff at the East African Herbarium in Nairobi; those from Ghana were identified by the late Albert Enti with duplicates deposited at the University of Ghana Herbarium in Accra. The specimens were collected and photographed during 1972, 1973 and 1976. The nomenclature follows the determinations made at that time except

(PDF) In vitro anti-HIV-1 properties of ethnobotanically

In vitro anti-HIV-1 properties of ethnobotanically selected South African plants used in the treatment of sexually transmitted diseases T.E. Tshikalangea,, J.J.M. Meyera, N. Lalla, E. Muñozb, R. Sanchob, M. Van de Venterc and V. Oosthuizenc a Department of Plant Science, University of Pretoria, Pretoria 0002, South Africa b Departamento de Biología Celular, Fisiología e Inmunología

In vitro antiplasmodial activity of medicinal plants

agents. The present study reports on the in vitro antiplasmodial activity of 134 plant taxa native to or naturalised in South Africa, representing 54 families, which were selected semi-quantitatively using weighted criteria. The plant extracts were tested for in vitro activity against a

Momona Ethiopian Journal of Science African Journals

In this study, the antimicrobial activity of three selected Ethiopian medicinal plants was studied with the objective of screening their antibacterial activity. The fruits of Measalanceolata,aerial part of Ci ssus quadrangularis and leaf of Dodonae angustifolia were collected, air dried under shed, powdered and soaked in 80% methanol and extracted. In vitro antibacterial activity of the

In vitro propagation, proscillaridin A production and

17/04/2013· Abstract. Drimia robusta is a threatened traditional medicinal plant extensively used in South Africa. Rapid in vitro mass propagation of the species was developed for commercial cultivation from leaf explants using various concentrations and combinations of plant

In vitro cytotoxicity of crude alkaloidal extracts of

In vitro cytotoxicity of crude alkaloidal extracts of South African Menispermaceae against three cancer cell lines H. De Wet1*, G. Fouche2 and F. R. Van Heerden3 1Department of Botany, University of Zululand, Private Bag X1001, KwaDlangezwa, 3886, South Africa. 2Bioprospecting, Biosciences, CSIR, P. O. Box 395, Pretoria, 0001, South Africa.

The anti-inflammatory and antioxidant activity of 25 plant

27/05/2015· Inflammation is a common risk factor in the pathogenesis of conditions such as infections, arthritis, type 2 diabetes mellitus, obesity and cancer. An ethnobotanical survey of medicinal plants used traditionally to treat inflammation and related disorders such as pain, arthritis and stomach aches in southern Africa led to the selection of 25 plant species used in this study.

Plants as a Source of Anti-Cancer Agents

I Plants as a Source of Anti-Cancer Agents G. M. Cragg and D. J. Newman Plant-Derived Anticancer Agents in Clinical Use (Figure 1) 3. Plant-Derived Anticancer Agents in Clinical Development (Figure 2) 4. Targeted Natural Products 5. Plant-Derived Antitumor Agents in Preclinical Development (Figure 3) 6. Cell Cycle Target Inhibition and Anticancer Drug Discovery 7. Conclusions

Evidence-Based Complementary and Alternative

Evidence-Based Complementary and Alternative Medicine (eCAM) is an international peer-reviewed, Open Access journal that seeks to understand the sources and to encourage rigorous research in this new, yet ancient world of complementary and alternative medicine.